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Endoscopic sphincterotomy (EST) carries several risks (e.g., pancreatitis and bleeding). The risk of bleeding is increased in patients with a compromised coagulation system, often due to antithromboembolic therapy. Recent guidelines caution to perform endoscopic procedures that carry a high risk of bleeding in these patients. However, data to support current recommendations are scarce, and EST frequently has to be performed as an emergency procedure.

Endoscopic biliary sphincterotomy in patients under antithromboembolic therapy.

Abdel Samie A, Dette S, Voehringer U, Sun R, Theilmann L


Take the Trip - A considerable amount of detailed information about Crohn’s disease and ulcerative colitis, the symptoms, the importance of accurate diagnosis, the treatments, the drugs and the critical aspects of all of this is presented in a manner that is easy to read and understand.


Doctors call for UAE-wide colorectal screening programme - Dr. Samie said red flags include anaemia, blood traces in stools, unintentional weight loss, difficulty swallowing and abdominal pains. He said there was a common misconception that a colonoscopy – a test that allows a doctor to look at the rectum and colon, take samples and remove abnormal growths – can be painful. "It is a simple and easy procedure and takes about 20 minutes."


Dr. Abdel Samie has authored more than 50 papers published in prestigious German and international medical journals, including pioneering research on anticoagulants and antiplatelet therapy in gastrointestinal endoscopy.


Proton pump inhibitors are frequently used to treat gastro-esophageal acid reflux and functional dyspepsia (a subgroup of irritable bowel syndrome/IBS).

A study conducted by Dr. A. Abdel Samie et al and published in Hepatogastroenterology showed that Proton pump inhibitor therapy may be associated with increased risk of recurrence of a severe bowel inflammation caused by a bacterium called clostridium difficile.

Risk factors for recurrence of clostridium difficile-associated diarrhoea.

Samie AA, Traub M, Bachmann K, Kopischke K, Theilmann L

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